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In particular, cocaine treatment in mice has been shown to cause a bidirectional loss of activity-dependent synaptic plasticity in the nucleus accumbens core, which is a defect in both LTP and LTD of excitatory synaptic transmission [114]

Agudelo M, Newton C, Widen R, Sherwood T, Nong L, Friedman H, Klein TW

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Various factors like certain diseases (e.g., autoimmune diseases, inflammatory states, and conditions affecting blood clotting) and cosmetic facial injections or fillers can also cause CRAO

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