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It is used to treat Vitamin B12 deficiency , megaloblastic anemia , and various neurological disorders , especially peripheral neuropathy

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3.1.3 Inhibiting chemotaxis A different strategy to alleviate neutrophilic inflammation focuses on directly reducing the influx of neutrophils into affected tissues

If you are not deficient in vitamin B12, then supplementation is unlikely to directly affect joint pain

Methylation happens when nutrients such as Folic Acid, Vitamin B6 and Vitamin B12 donate a methyl group (a molecule combo of one carbon and three hydrogen), and transfer it to a protein, enzyme, hormone or right onto DNA