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Acknowledgements We thank the Ilonka Kraft-Oberbeck, Ines Dobias and Nicola Lmmle for their excellent field work, Gerlinde Trischler for expert technical assistance and Gertrud Feike, Sarah Enderle, and Birgit Och for excellent data management and technical support

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As the cost of single-cell sequencing is relatively expensive at present, the sample size studied is small

The COX17 transports copper to CCO (51, 52)

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