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Zeng XT, Tu ML, Liu DY, Zheng D, Zhang J, Leng W: Periodontal disease and risk of chronic obstructive pulmonary disease: a meta-analysis of observational studies

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Future research should focus on large-scale, well-controlled randomized trials with standardized dosing protocols, clearly defined deficiency thresholds, and long-term follow-up to strengthen the evidence base and guide clinical practice