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It is also possible to increase the expression of neuroprotective factors in the body through gene therapy or drugs, such as Brain-Derived Neurotrophic Factor (BDNF) and Glial Cell Line-Derived Neurotrophic Factor (GDNF), thereby enhancing the survival ability of neuronal cells and extending the lifespan of ALS patients (56)

Erastin exploits the defective mitophagy-driven ROS accumulation to circumvent the ferroptosis resistance characteristic of EESCs, thereby enhancing its therapeutic efficacy

Boswellia green mailnly reduces acute inflammatory reactions, improves skin firmness and modulates the barrier function

The most common identifiable cause is varicocele, enlarged veins in the scrotum that raise testicular temperature and impair sperm production, found in approximately 35-40% of men with primary infertility

Iron transporter Nramp2/DMT-1 is associated with the membrane of phagosomes in macrophages and Sertoli cells