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Mol Biol Rep 39:817824 Guruprasad K, Reddy BB, Pandit MW (1990) Correlation between stability of a protein and its dipeptide composition: a novel approach for predicting in vivo stability of a protein from its primary sequence

H.SchildhornC.JacobiC.HommeM.HartnerA.BraunH.et al (2010)

Their method was direct

Reported side effects include: Nausea and queasiness , especially after meals during the first few weeks of dosing