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Researchers investigated the iron accumulation in the brains of VCID patients caused by subcortical ischemia using QSM technology and discovered that the iron accumulation is widespread in the patients brains and is closely related to damage in different cognitive areas (Sun et al., 2017)

Free radicals are unstable molecules that can lead to oxidative stress and contribute to various chronic diseases, such as heart disease, cancer, and certain neurological disorders

During a vitrectomy, portions of the vitreous containing the floater are removed

J Neuroimmunol 93:7280 Raybould HE, Tach Y (1989) Capsaicin-sensitive vagal afferent fibers and stimulation of gastric acid secretion in anesthetized rats

mGluR5 acts as an important cofactor, its chronic activation can enhance NMDA receptors (NMDARs) activity and further amplify neuronal excitotoxicity [37]