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Front Psychiatry 2023;14:1065812

supporting the survival of exogenous cells and remaining NPCs in the intervertebral disc

Yamaza H, Komatsu T, Wakita S, Kijogi C, Park S, Hayashi H et al

Metabolic reprogramming driven by oncogenes allows cancer cells to maintain deregulated cell proliferation, withstand metabolic challenges that are associated with diminished oxygen and nutrients, maintain a dedifferentiated state through alterations in global patterns of gene expression, and corrupt the surrounding microenvironment to actively facilitate tumor growth and dissemination 16,17,18