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Cell culture Human MM cell lines MM.1S, RPMI-8226, U266 and NCI-H929 were from ATCC (Manassas, VA, USA) and MOLP-2, KMS-12-PE, OPM-2 and EJM were from DSMZ (Braunschweig, Germany)

Pathological Hallmarks of Alzheimer Disease A formal diagnosis of AD requires the presence of both senile plaques, which are composed of aggregated fibrils of A (mostly 42 and 40 amino acids in length) together with dystrophic neurites and neurofibrillary tangles, which are composed of aggregates of hyperphosphorylated Tau protein (98, 99)

Cysteine residues are among the most easily metabolized compounds, being easily oxidized by transition metals and participating in thiol-disulfide exchange reactions

Furthermore, Ze450 has been shown to be protective against cellular peroxidation, where Ze450 retains mitochondrial function and integrity by inhibiting ferroptosis

vehicle, two-way ANOVA, for interaction factor, P =0.9693) (Fig