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doi: 10.3389/fphar.2021.636154 120 ZhouYFangLJiangLWenPCaoHDHeWCet al

Drug Development Research , 80 , 360367

Studies have suggested mechanisms regarding the interaction between the microbiota and the gut-brain axis

Moreover, the metabolites of arginine play an important role in maintaining the intestinal barrier and promoting the repair of the gastrointestinal mucosa ( + cells and activate CD4 + T lymphocytes, leading to inflammatory/immune-mediated diseases ( + /CD8 + in different parts of intestinal mucosal immunity decreased significantly after 8 weeks of TGP administration in this study, suggesting that TGP may regulate lymphocytes in intestinal mucosal immunity and epithelial barrier through glutathione metabolism, thereby exerting an anti-RA effect