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Cones (6-7 million per eye) handle color and detailed vision, concentrated in macula

Although analgesics such as NSAIDs are widely used for pain control, they cause some adverse reactions such as upper gastrointestinal bleeding [1, 2, 3]

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However, it's essential to exercise caution to avoid acquiring low-quality compounds that may be unsafe or ineffective for research purposes

Upon ligand binding, TLRs recruit adaptor proteins primarily MyD88 or TRIF which activate downstream kinases including IRAKs and TRAF6, leading to the stimulation of transcription factors NF-B, AP-1, and IRF family members [33]