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10.1038/tp.2013.14 9 FryeR

In Mepron pellets, Met and starch are coated by ethyl-cellulose and stearic acid, which releases Met slowly over time by abrasion and physical force in the intestine (Schwab and Ordway, 2003)

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These changes correlate with increased GSH levels and decreased ACSL4 expression, thus mitigating ferroptotic cell death in IL-1stimulated chondrocytes and preserving cartilage integrity (187)