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Similarly, the gut microbiota member Fusobacterium nucleatum and its product succinic acid confer resistance to anti-PD-1 mAb by inhibiting the cGAS-interferon- pathway, thereby impairing CD8+ T cell-mediated anti-tumor immunity in the CRC

Factors Influencing Dosage Several factors can influence how much glutathione one should take, including: Age: Older adults may require higher doses due to decreased natural production