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Decades of dismissal have left these conditions poorly understood, meaning over two thirds of R&D funding is being spent on basic research

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Moreels TG, Nieuwendijk RJ, De Man JG, et al

Furthermore, the pharmacological induction of HSP expression with geranylgeranylacetone (GGA) is antiarrhythmic in both in vitro HL-1 cells and in vivo dogs, and oral GGA treatment has been shown to induce atrial HSP expression in humans undergoing cardiac surgery Figure 7