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Prior study showed that deficiency of Sentrin/SUMO-specific protease 2 (SENP2) resulted in hyper-SUMOylation of multiple potassium channels and neuronal hyperexcitability, finally triggering spontaneous seizures and sudden death [78, 79], which suggests that sumoylation is vital for epilepsy

Statistical differences in glutathione, glutamate measurement and miniature EPSC analysis were done by Tukey-Kramer HSD test, except where noted

Conditions such as rheumatoid arthritis (RA), systemic lupus erythematosus (SLE), multiple sclerosis (MS), Hashimotos thyroiditis, and coeliac disease are commonly associated with symptoms including joint pain, digestive disturbances, and fatigue commonly seen in autoimmune conditions (46)

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A healthy liver is vital for overall skin health, as it helps to eliminate substances that can negatively affect our skin