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Mice with a deficiency of key components in the NF-B pathway die as a result of massive hepatocyte apoptosis induced by TNF 37,38 , supporting the critical role of maintenance of hepatocyte NF-B pathway in protecting against TNF cytotoxicity

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C auris s precise detection via TaqMan realtime PCR assay is an important diagnostic tool (322)

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Enhancement of purine nucleotide synthesis via the pentose phosphate pathway was found to be advantageous for cell proliferation and tumorigenesis of NRF2-addicted cancer cells (Mitsuishi et al