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Some physicians would start colchicine after one very severe or two moderately severe attacks of gout, and beyond that, use allopurinol

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Our body composition, including how much fat and muscle we have, influences the fluid volume in our body since muscle contains more water than fat

While she believes that the anti-inflammatory and reparative benefits outweigh the risks for short-term use, she wouldn't put someone on it indefinitely

It works on the output side of the energy balance equation: it modifies how the body handles the fat tissue once the caloric environment has produced a deficit