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Nat Commun (2020) 11(1):1875

313 The optimized successor of GKT137831, Setanaxib, overcomes PD-1/PD-L1 resistance by targeting NOX4 in cancer-associated fibroblasts, reversing their immunosuppressive phenotype, and enhancing CD8 + T-cell infiltration

Greiner JW, Zeytin H, Anver MR, Schlom J

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(2019) and Of importance, ox-LDL and macrophages are involved in the whole process of atherosclerosis from plaque initiation to plaque progression, rupture, or even regression (Liu et al., 2021a