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Step 5: Gently Mix Do not shake the vial

doi: 10.1016/j.pbi.2010.11.005 30 DiC.YuanJ.WuY.LiJ.LinH.HuL.et al

et al.: Methylmalonic acid in aging and disease (2024) Trends in endocrinology and metabolism: TEM | DOI: 10.1016/j.tem.2023.11.001.

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At the molecular level, copper directly interacts with A and tau proteins, facilitating their abnormal aggregation, enhancing neurotoxicity, and promoting both A deposition and tau hyperphosphorylation, ultimately leading to neuronal dysfunction and injury (185)