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Perkins BA et al

Holvoet P, Laroche Y, Lijnen HR, Van Hoef B, Brouwers E, De Cock F, Lauwereys M, Gansemans Y, Collen D: Biochemical characterization of single-chain chimeric plasminogen activators consisting of a single-chain Fv fragment of a fibrin-specific antibody and single-chain urokinase

In the concealed platform assessment, the mean escape delay was documented for each cohort of rats during a 5-day duration

These are, however, general estimates, and there are nuances to each regulatory pathway that can affect the length of time the FDA's medical device approval process takes