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A thermostable oxidation-reduction system (Hopkins FG, Dixon M (1922) J Biol Chem 54 527563)

As a result, patients may experience a significant burden from deficiencies

Both I2 and HOI iodinate specific tyrosyl residues of the thyroglobulin within the colloid to form 3-monoiodityrosyl (MIT-yl) and 3,5-diiodityrosyl (DIT-yl) residuesintroducting iodine atoms at one or both locations ortho to the hydroxyls of tyrosine