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10.1371/journal.pone.0003554 PLoS One 220 SandersE

it is produced primarily through bacterial fermentation in the gastrointestinal tract and, to a lesser extent, in human cells under specific pathological conditions [21, 22]

Glucagon-like peptide 1 (GLP-1): a potent gut hormone with a possible therapeutic perspective

7, 8, 9, 10 As an example, mast cells are involved in autoimmune disorders and many of the proinflammatory and tissue destructive mediators produced by these cells have been directly implicated in the pathogenesis of rheumatoid arthritis and other rheumatic diseases

We performed highresolution confocal microscopy and observed that CEST2.2 O/E was also sufficient to ameliorate the aberrant mitochondrial fragmentation in the gut of gas1 mutant nematodes (Fig 2H), indicating a better maintenance of the mitochondrial network