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However, isolated ketone, hydroxyl, methoxy, or ortho-methoxy groups are not associated with the chelation of iron at all ( TABLE 2 Iron binding sites of flavonoids

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The role of NRF2 has been confirmed beyond initial assumptions, presenting both challenges and opportunities in cancer treatment [69]

These data suggest that in chronic alcoholics with liver disease, GSH deficiency exists, which may predispose to further liver toxicity caused by resultant inadequate defense mechanisms