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Functional inactivation of the IGF-I and insulin receptors in skeletal muscle causes type 2 diabetes

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Among these, sesquiterpene farnesol, which is present in many essential oils, has demonstrated the ability to potentiate the activity of beta-lactam antibiotics against Burkholderia pseudomallei

SUMO precursors are cleaved by specific peptidases to expose the C-terminal diglycine motif, and the mature SUMO is then activated by an E1 enzyme in an ATP-dependent manner

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