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After an 1 h of magnetic stirring at room temperature, P3 (300 mg) was introduced into the reaction system

Prolonged exposure to hydroquinone has been associated with a range of adverse effects, including irritative dermatitis, melanocyte destruction, contact dermatitis, neuronal damage, and mutations 4,21,26,27,28

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Participants either followed an exclusion diet, defined as gluten and casein free regimen adopted independently by families before enrolment, or an unrestricted die, an important source of baseline heterogeneity, as dietary patterns were not experimentally assigned

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