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ML performed the statistical analysis

52 Class I variants have very severe enzyme deficiency (less than 10% to.20% of normal) and have chronic hemolytic anemia

PHGDH-mediated biosynthesis of serine is also essential for M2 macrophages metabolism, promoting -ketoglutarate synthesis and mTOR activity

There is research underway into ways that we can detect the disease at the earliest time points, so that we will be less likely to see patients like the first one I met