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442C In chemico skin sensitization: assays addressing the adverse outcome pathway key event on covalent binding to proteins

ALS clinical trials have also incorporated advanced electrophysiologic studies as exploratory outcomes measures for quantifying lower and upper motor neuron function, although they are limited by generalizability and interrater reliability [63, 64]

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Among 33 non-treated patients, 16 (48%) were lost to follow-up, 8 deferred treatment (3 undergoing cancer treatment, 3 awaiting kidney transplantation, 2 with ongoing substance use), 3 were referred elsewhere, 2 deceased, 2 relocated, 1 was denied prior-authorization, and 1 declined treatment