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In a study by Sahin et al., rats with induced AR were orally treated with naringenin for 7 days

Molecular Pharmaceutics 5 (2008) 739-744

Prx and GPx require secondary enzymes and cofactors to function efficiently and regulate the cytoplasmic redox system (Chae et al., The overall cellular redox state is determined by two cellular disulfide reductase systems (Das and White, 2002