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The miR-491-5p/IGF2 interaction was also confirmed by the finding that IGF2 overexpression partially reverted the anti-tumor effects of miR-491-5p (103)

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Biological actions of GLP-1, source: reference [1] Evolution of GLP1 GLP-1RAs Currently, there are nine GLP-1RAs approved for marketing worldwide (Table 1), mainly for the treatment of diabetes and obesity, of which tirzepatide is a novel dual GLP-1RA/GIPR agonist