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Description

The non-immune mechanism mainly involves the metabolic reaction of drugs: direct and indirect damage to hepatocytes

These are derived from the female plant of Cannabis sativa L (family Cannabinaceae)

phosphodiesterase, PDE

10.1038/srep28484 76 ChenX.XuL.ChenQ.SuS.ZhuangJ.QiaoD

We already showed that DZnep analogs increase SAH in mammalian cells 6 , but to confirm that DZnep does increase SAH also in the green plant clade, we quantified SAM and SAH in DZnep-treated algae and revealed a dose-dependent increase in SAH and a decrease in methylation potential (Fig