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The loss of blood supply led to the decrease in the number of proliferating tumor cells

Nevertheless, metal oxide doses administrated at 1mg/kg in a single dose need proper safety profile investigation for use in clinical settings [187]

[9] Coppers toxicity mechanism is well characterised: free or loosely bound Cu(II)/Cu(I) participates in Fenton-type redox chemistry, generating hydroxyl radicals that damage lipids, proteins, and DNA

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