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Increased levels of ROS may result from the buildup of abnormal proteins and malfunctioning mitochondria in tissues lacking autophagy [70, 71]

And last of all, bear in mind that certain skin types have a greater disposition than others to this type of darkening of the area, in particular darker phototypes

The production of ROS triggered by radiation activates downstream NLRP3 inflammatory vesicles, resulting in increased production of IL- by lung epithelial cells, which directly affects the transformation of fibroblasts into myofibroblasts

In the case of vesicle trafficking, anthocyanins are sequestered in vesicle-like structures derived from endoplasmic reticulum and later fused into the vacuole via cytoskeleton-binding proteins (e.g., GFS9

Furthermore, these authors demonstrated that TWIST1 expression levels can predict the therapeutic function of a given MSC population