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These treatments employ iron oxide NPs combined with the knockout of seven ferroptosis resistance genes ( FPN , LCN2 , FTH1 , FSP1 , GPX4 , SLC7A11 , and NRF2 ) to construct a powerful ferroptosis-inducing vector, which has demonstrated tumor-specific killing power in various cancer models, including BC(Luo et al

Nashimoto et al., 2020)

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1 2 "The mechanism of action of N -acetylcysteine (NAC): The emerging role of H 2 S and sulfane sulfur species"