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A 128 % rise in GSH levels and a 66 % rise in the GSH/GSSG ratio were noted

In a multivariate analysis including PNPLA3 GG allele, FADS1 TT allele, FADS2 TT allele, etiology, age, and sex, only the TT allele of FADS2 was an independent risk factor for advanced fibrosis (P=0.011)

This study was supported by the Zhejiang Provincial Health Commission (2025KY1506), the Natural Science Foundation of Zhejiang Province (KLY25H160064), the Basic Public Welfare Research Project of the Wenzhou Municipal Science and Technology Bureau (Y20240109), and Zhejiang Clinovation Pride

doi: 10.1111/pcn.12175 54 ChenKTWuCHTsaiMHWuYCJouMJHuangCCet al

Chemical synthesis via SPPS is crucial for these modifications, enabling precise sequence control, improved stability, and exploration of structure-activity relationships ( 4.1 Incorporation of unusual amino acids Chemical synthesis of AMPs offers advantages over natural extraction, enabling precise sequence modification via solid-phase peptide synthesis (Pazgier et al., 2006