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In gMG, in contrast, anti-AChR IgG1 and IgG3 cause immune activation against the neuromuscular junction, which leads to distorted membrane folding and a reduced amount of AChR

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Drugs acting on the renin-angiotensin system are involved in the NF-B and MAPK signaling pathways and reduce the expression of inflammatory factors such as IL-4 and TNF-