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This happens because activating melanocyte receptors (MC1) stimulates melanin production

It is commonly found in various foods including onions, grapes, berries, cherries, broccoli, tea, lemon, tomato, onion leaves, strawberries, and citrus fruits [145]

The loss of SLC7A11 substantially abolishes tumorigenesis while the overexpression of SLC7A11 promotes tumor development through ferroptosis resistance [62]