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Clear Development Challenges and Optimization Directions Currently, the preparation still has obvious limitations

Understanding this distinction could provide valuable insights into the mechanisms of their interaction and their potential impact on health outcomes

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This was most recently shown by such studies as ASCEND (A Study of Cardiovascular Events in Diabetes) [71], STRENGTH (Long-Term Outcomes Study to Assess Statin Residual Risk with Epanova in High Cardiovascular Risk Patients with Hypertriglyceridemia) [72], OMEMI (Omega-3 fatty acids in Elderly with Myocardial Infarction) [73] and VITAL (Vitamin D and Omega-3 Trial) trials [74]

Notably, the efficacy of dietary restriction is tumor-specific: it only exerts potent effects on tumors highly dependent on the SSP, while showing limited efficacy in tumors with low SSP dependence or those capable of compensatory activation of the endogenous SSP (102)