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The capillary lymphatic vessels exhibit incomplete intercellular junctions, thereby enabling the transport of interstitial fluid via a process influenced by the mechanical expansion instigated by skeletal muscle movements and lymphatic drainage

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It was proposed that such oxidation-dependent modifications of SR-B1 subcellular localization and stability might affect the physiological uptake of cholesterol by SC epidermal cells, which, in turn, might compromise their lipid composition and barrier function in the course of oxidative stress (Sticozzi et al., 2012)

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2285-C CHOLESTEROL-ASSOCIATED LOCUS EHBP1 PROTECTS AGAINST NASH FIBROSIS Fanglin Ma and Bishuang Cai, Icahn School of Medicine at Mount Sinai Background: Elevated hepatic cholesterol content is frequently seen in human NASH and high-cholesterol diets have been found to promote NASH progression in mouse models