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The reactivity toward DTNB (50 M) was followed spectrophotometrically at 412 nm where TNBS - absorbs ( TNBS - = 11800 M 1 cm 1 at pH 5.0) in 0.1 M sodium acetate buffer pH 5.0, 0.12 M urea (25 C)

Access this article Similar content being viewed by others References Aithal GP, Ramsay L, Daly AK, Sonchit N, Leathart JB, Alexander G, Kenna JG, Caldwell J, Day CP (2004) Hepatic adducts, circulating antibodies, and cytokine polymorphisms in patients with diclofenac hepatotoxicity

Data availability All data supporting the findings of this study are available within the manuscript and its Supplementary Information files

Nonetheless, many clinical investigations are limited by short follow-up durations, small sample sizes, heterogeneous formulations, and reliance on surrogate endpoints, such as variations in bacterial diversity or inflammatory markers, rather than definitive clinical outcomes, thereby limiting the robustness of current conclusions (2, 4)

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