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Evaluation of the bactericidal activity of fosfomycin in combination with selected antimicrobial comparison agents tested against gram-negative bacterial strains by using time-kill curves

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Such information and supporting documentation include the following: (i) Evidence that the severe supply chain disruption directly affects the manufacturer itself, a supplier of an ingredient or packaging, a contract manufacturer, or a method of shipping or distribution that the manufacturer uses to make or distribute the Part B rebatable biosimilar biological product(s), such as a change in the production or distribution of the Part B rebatable biosimilar biological product(s) that is reasonably likely to lead to a significant reduction in the U.S

This includes, in particular, the NO-system [11,29,92,93,94,97,98,99] as a whole

doi: 10.1038/s41586-019-0985-x 92 BoomerJSToKChangKCTakasuOOsborneDFWaltonAHet al