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The loss of dopaminergic neurons is also exacerbated by oxidative stress triggered by H 2 O 2 produced by MAO-B activity 539

That short window is a feature, not a bug, when researchers want to isolate a single GH pulse from background

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Int J Mol Sci 24(1):388 Zhang C, Dulinskas R, Ineichen C, Greter A, Sigrist H, Li Y, Alanis-Lobato G, Hengerer B, Pryce CR (2024) Chronic stress deficits in reward behaviour co-occur with low nucleus accumbens dopamine activity during reward anticipation specifically