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Notably, the alleviation effect of RA in the mouse model by SP@M was comparable to, or even better than that by MTX used in clinical practice (Fig

Plant Physiol 144:17151732 Maughan SC, Pasternak M, Cairns N (2010) Plant homologs of the Plasmodium falciparum chloroquine resistance transporter, PfCRT, are required for glutathione homeostasis and stress responses

The hyper-aggregability observed in these diseases appears to be related to higher platelet reactivity towards agonists or increased circulation of these agonists (such as thrombin and factor Xa), and is a primary cause of thrombotic events, in particular venous thromboembolism events (VTE) and arterial thrombosis (AT) [112, 113]

It possesses a variety of pharmacologic actions and has the potential to be used in patients suffering from PCOS (88)