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In: Hergovich, A

Anti-Seizure Drugs: These may contribute to melasma through hormonal effects or increased skin reactivity

More recently, a breakthrough 2026 study utilizing both in-vitro cellular models and an in-vivo human pharmacokinetic trial further solidified these findings

doi: 10.1007/978-94-007-2199-9_7 25 LauerAAGrimmHSApelBGolobrodskaNKruseLRatanskiEet al

The toxic effects of this amino acid may arise from the production of free radicals, which occurs when Hcy undergoes autooxidation to form Hcy disulfide or when it forms mixed disulphides with other thiols