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Mittal, M., et al., Reactive oxygen species in inflammation and tissue injury

Chem Res Toxicol 30:1337 Faizan S, Mohsen MMA, Amarakanth C et al (2024) Quinone scaffolds as potential therapeutic anticancer agents: Chemistry, mechanism of Actions, Structure-Activity relationships and future perspectives

Compared with its homolog MFN2, MFN1 exhibits higher GTPase activity and relies more extensively on GTP hydrolysis to facilitate membrane fusion ( Under 4-HNEinduced lipid peroxidation, mitochondrial dynamics shift toward excessive fission