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doi: 10.1038/s41598-020-62136-2 473 KatoKNaganeMAiharaNKamiieJMiyanabeMHirakiSet al

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The comprehensive metabolic profile was reviewed by physicians and compared to known reference ranges

PMC 1874596

This occurs as a result of mistreatment of the protein alpha-synuclein and its aggregated forms and also as a result of the gradual loss of nigrostriatal neurons [46]