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Furthermore, mutants had severely diminished proliferation in brain tissue, which was colonized in less than half of mutant-infected mice (Extended Data Fig

Old matrix components are degraded, new proteins are synthesized, and cellular populations reorganize in response to changing physiological demands

For a long time, the antineoplastic effects of cisplatin have been fully ascribed to its ability to generate unrepairable DNA lesions, hence inducing either a permanent proliferative arrest known as cellular senescence or the mitochondrial pathway of apoptosis

Both GLS silencing and GLS2 overexpression synergize with oxidative stress against proliferation of glioma cells

In addition, many of vitamin B12s biological effects are tied to its involvement in supporting normal nervous system function