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35 were animal studies

Lipid droplet-associated mitochondria exhibit increased fatty acid oxidation, as indicated by elevated levels of phosphorylated ACC2 (pACC2), Mitofusin 2 protein (MFN2) and CPT1 activity, but are damaged by fatty acid oxidation in an NAFLD rat model [56]

Functional complementary DNA clones were assembled and shown to be infectious by direct intrahepatic injection of RNA transcripts into chimpanzees 52,53