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The same authors also showed [59, 70] that the action of both CAT and GPx was insufficient to explain the erythrocyte oxidative catabolism, and proposed [70] a model including Prx2 that, in accordance with their experimental data, could better explain the erythrocyte antioxidant defense system

Moreover, intestinal microorganisms and their biochemical properties influence the bioavailability and metabolism of selenium [97]

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The paucity of data on specific enzyme pathways and differences in study populations may affect the applicability of the findings