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A larger follow-up RCT (n=72 older adults) confirmed these findings, additionally demonstrating improvements in gait speed (+0.14 m/s), grip strength, 6-minute walk distance, waist circumference reduction, and systolic blood pressure reduction (Kumar et al., J Gerontol A Biol Sci Med Sci, 2023) [21]

Although earlier studies suggest no agerelated decline in GH responsiveness to GHRH, more recent reports indicate a gender-independent, age-related decline in acute GH responsiveness to GHRH and ghrelin (16)

It is marketed under the brand name Egrifta (tesamorelin for injection) at a dosage of 2 mg subcutaneous injection daily

Safety and metabolic effects of tesamorelin, a growth hormone-releasing factor analogue, in patients with type 2 diabetes: A randomized, placebo-controlled trial

Growth hormonereleasing peptides have exploded in popularity among bodybuilders, biohackers, and recovery-focused athletes and for good reason