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As we previously published, a multiweapon approach is needed to successfully combat SARS-CoV-2 and COVID-19 disease (Labarrere and Kassab, 2021), involving vaccines (Jin et al., 2022) especially vaccines that selectively and efficiently induce antibodies that target the SARS-CoV-2 receptor binding domain (Robbiani et al., 2020), pattern recognition proteins such as surfactant proteins A and D (Arroyo et al., 2021

Treatment with SUN (25 mg/kg/day) for 28 successive days resulted in a significant 187% and 79% increase in mRNA expression and protein level of ACC2 in rat heart tissues, respectively, as compared to the control group

Inhibition of the enzymes responsible for glucose starvation and glycolysis [hexokinase (HK), lactate dehydrogenase (LDH), etc] as well as inhibition of the efflux of lactate (the end product of glycolysis) are also effective